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Afatinib is a drug typically used to treat non-melanoma skin cancer. It belongs to the kinase inhibitor group of drugs.

It works by interfering with melanin production in the skin. Melanin is responsible for the pigment of your skin. As we know, melanin protects the skin from damage and hence it is very important. But it is also one of the causes of skin cancer. The melanocytes are present in the dermis or the second layer of the skin. They produce melanin either from a food source or from the surrounding tissues.

The drug works by interfering with the function of the melanocytes. The melanocytes produce melanin either in response to stimuli or as a permanent process. This drug makes the melanocytes stop producing at the middle of the process. Hence the melanin production of the area where the drug has been applied is normalized. This results in inhibition of cancer formation in this particular skin cancer.

One of the advantages of using this drug is that it inhibits cancer at its earliest stage. In other words, it delays the growth of the tumor. Another advantage is that it does not show any effects. Afatinib-bibw2992 is known to inhibit melanoma, squamous cell, head and neck cancer. It also shows some signs of improving survival in patients who have melanoma.

However, there are some limitations of Afatinib too. One of these is that, it only works on people with light skin. It may cause a severe rash in such patients. In addition, the treatment requires prolonged use. The dosage of Afatinib is one of the factors that affect the effectiveness of this treatment. So while buying this product one must make sure of the suggested dosage of this drug.

Afatinib is taken orally. But it can also be used in injection form for the treatment of melanoma. It is also available in the form of capsules and liquid solutions. The …

Today, there are lots of beer companies, and a look at the history of beer would help appreciate the origin and the evolution of beer with time and how these companies came to be. A look at reviews of the specific companies such as beer52 review will help identify reputable beer companies that one can purchase from. Consumption of beer should always be accompanied by a fitness routine and a healthy diet, looking at reviews related to healthy diets will help one select the best fitness and diet companies to shop from. Man has practised beer brewing from the earliest known period. Ancient Babylonians and Egyptians cultivated grains of barley from as early as 6000BC. At first, brewing happened by accident when barley loaves that had been left on the rain fermented. The brew was then flavoured with honey before it was drunk. Ancient Egyptians even utilized beer as a currency. The spread of Islam at around 800AD would abolish the brewing of beer in Egypt. This article gives the evolution of the beer in the UK.

Before it became a lucrative trade that monks in abbeys and monasteries took advantage of beer in Britain was brewed in people’s households. When monks started brewing, beer, it became more intricate, especially when flavours and preservatives were incorporated. In this early days, beer was a safer option to drink than water, and thus the primary function of beer consumption was to hydrate the body.

Today’s fast forward move to the British beer industry shows dramatically different aspects from those of the beer brewed traditionally. For an extended period, beer was a functional beverage that has now evolved into segments such as the craft category. Beer accounts for about half of the sales of trademark drinks, then spirit follows at about 25%, champagne and wine at 16.9%and the cider at 7.5%. The beer category is hugely dominated by lager at 69%.

Beer over

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Who doesn’t know dragon fruit? Its unique shape and delicious taste make this fruit attractive for consumption. Dragon fruit also has several variants, some are white and some are reddish-purple.

Besides being delicious, the benefits of dragon fruit are quite diverse. You may not have known about these health benefits before.

Here are health benefits of dragon fruit:

 

1. Rich in fluid content

Even though it lives in dry areas, the liquid content of dragon fruit is quite high. This makes dragon fruit one of the benefits of preventing dehydration, as well as providing a sensation of freshness when consumed.

This fresh sensation is what makes people like to eat dragon fruit, whether eaten directly, made juice, or mixed with other fruits as fruit ice.

 

2. Source of Iron

The benefits of dragon fruit are indeed extraordinary, one of which is a source of iron for the body. One hundred grams of dragon fruit contains 1.9 milligrams of iron or the equivalent of 11 percent of the total daily needs of adults.

 

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